• Proteases in plasma and kidney of db /db mice as markers of diabetes-induced nephropathy 

      Hadler-Olsen, Elin Synnøve; Winberg, Jan-Olof; Reinholt, Finn P.; Larsen, Terje; Uhlin-Hansen, Lars; Jenssen, Trond Geir; Berg, Eli; Kolset, Svein Olav (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      Db/db mice are overweight, dyslipidemic and develop diabetic complications, relevant for similar complications in human type 2 diabetes. We have used db/db and db/+ control mice to investigate alterations in proteinase expression and activity in circulation and kidneys by SDS-PAGE zymography, electron microscopy, immunohistochemistry, Western blotting, and in situ zymography. Plasma from db/db mice ...
    • Systemic inflammation early after kidney transplantation is associated with long-term graft loss: a cohort study 

      Heldal, Torbjørn Fossum; Åsberg, Anders; Ueland, Thor; Reisæter, Anna Varberg; Pischke, Soeren; Mollnes, Tom Eirik; Aukrust, Pål; Reinholt, Finn P.; Hartmann, Anders; Heldal, Kristian; Jenssen, Trond (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-10-02)
      Background: Early graft loss following kidney transplantation is mainly a result of acute rejection or surgical complications, while long-term kidney allograft loss is more complex. We examined the association between systemic inflammation early after kidney transplantation and long-term graft loss, as well as correlations between systemic inflammation scores and inflammatory findings in biopsies 6 ...